Yearly Archives: 2021

News: Study shows antibody growth from AstraZeneca, Sputnik Light COVID-19 vaccine mix

A small-scale clinical study of the combined use of the AstraZeneca and Sputnik Light vaccines against COVID-19 has shown strong antibody growth in a majority of the study’s participants, the Russian Direct Investment Fund said on Monday.The data was collected from 20 people who took part in a 100-person study in Azerbaijan that began in February. They first received the AstraZeneca shot followed by the one-dose Russian-made Sputnik Light shot 29 days later, RDIF said.“According to the results of the interim analysis, a fourfold or higher increase in neutralising antibodies to the spike protein (S-protein) of the SARS-CoV-2 was found in 85% of the volunteers on the 57th day of the study,” RDIF said.The post Study shows antibody growth from AstraZeneca, Sputnik Light COVID-19 vaccine mix appeared first on ARY NEWS.from ScienceTechnology – ARY NEWS https://ift.tt/3EStF6V https://ift.tt/eA8V8J

A small-scale clinical study of the combined use of the AstraZeneca and Sputnik Light vaccines against COVID-19 has shown strong antibody growth in a majority of the study’s participants, the Russian Direct Investment Fund said on Monday.

The data was collected from 20 people who took part in a 100-person study in Azerbaijan that began in February. They first received the AstraZeneca shot followed by the one-dose Russian-made Sputnik Light shot 29 days later, RDIF said.

“According to the results of the interim analysis, a fourfold or higher increase in neutralising antibodies to the spike protein (S-protein) of the SARS-CoV-2 was found in 85% of the volunteers on the 57th day of the study,” RDIF said.

The post Study shows antibody growth from AstraZeneca, Sputnik Light COVID-19 vaccine mix appeared first on ARY NEWS.

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News: Windows 11 gets an update for the better experience of Android users

Your Phone software by Microsoft, which serves as a bridge between Android devices and Windows 10, is all set to get a makeover for Windows 11.While things do not seem to have changed dramatically like new functionality is on the cards in the short term, we know a bit into the app at Microsoft’s recent Surface event as it still reminds us of its existence.Your Phone app, too, gets a new look as do the other apps updated for Windows 11, with softer set of colors and rounded corners. However, it’s in the interface where the real improvement lies.If you go into the app right now, you’ll see separate sections for Notifications, Messages, Calls. Also, Apps if you own a supported Samsung device or a Surface Duo. With the new version, XDA Developers spotted that notifications now feature along the left-hand side of the app, with can respond directly from your desktop or laptop.Other items to have been relocated are Messages, Photos, Apps and Calls that now appear at the top of the screen. The now little less cluttered look should make the app a bit more accessible to newcomers. Although, it can be a bit confusing to those who have got used to the current layout.From this brief glimpse it’s encouraging to see that the app hasn’t been forgotten about even if it doesn’t get so many changes, and while it’s understandably not as impressive as the synergy between iPhones and Macs (where things like iMessage and Photos are always in perfect sync), it’s still useful for those that spread their working life across form factors.And with Microsoft fully on board with Android, having waved the white flag on Windows Phone some time ago, a lot more people can benefit.Is it necessary?Many have reportedly said they installed the Your Phone software for Windows 10 upon release, but haven’t booted it up again since. Why? Because the stuff they thought they needed it for already has perfectly good systems in place.But for some it will prove invaluable, and that — combined with the upcoming Android app support for Windows 11 — makes Microsoft’s OS a natural home for Android users.Microsoft Windows 11 will be released on October 5 as a free upgrade to Windows 10, but the rollout is going to be staggered, so don’t expect to see it on your screen immediately unless you buy a new device — such as Microsoft’s own Surface Pro 8, Surface Pro X, Surface Go 3 or the innovative new Surface Laptop Studio.

Microsoft window 11


Your Phone software by Microsoft, which serves as a bridge between Android devices and Windows 10, is all set to get a makeover for Windows 11.

While things do not seem to have changed dramatically like new functionality is on the cards in the short term, we know a bit into the app at Microsoft’s recent Surface event as it still reminds us of its existence.

Your Phone app, too, gets a new look as do the other apps updated for Windows 11, with softer set of colors and rounded corners. However, it’s in the interface where the real improvement lies.

If you go into the app right now, you’ll see separate sections for Notifications, Messages, Calls. Also, Apps if you own a supported Samsung device or a Surface Duo. With the new version, XDA Developers spotted that notifications now feature along the left-hand side of the app, with can respond directly from your desktop or laptop.

Other items to have been relocated are Messages, Photos, Apps and Calls that now appear at the top of the screen. The now little less cluttered look should make the app a bit more accessible to newcomers. Although, it can be a bit confusing to those who have got used to the current layout.

From this brief glimpse it’s encouraging to see that the app hasn’t been forgotten about even if it doesn’t get so many changes, and while it’s understandably not as impressive as the synergy between iPhones and Macs (where things like iMessage and Photos are always in perfect sync), it’s still useful for those that spread their working life across form factors.

And with Microsoft fully on board with Android, having waved the white flag on Windows Phone some time ago, a lot more people can benefit.

Is it necessary?

Many have reportedly said they installed the Your Phone software for Windows 10 upon release, but haven’t booted it up again since. Why? Because the stuff they thought they needed it for already has perfectly good systems in place.

But for some it will prove invaluable, and that — combined with the upcoming Android app support for Windows 11 — makes Microsoft’s OS a natural home for Android users.

Microsoft Windows 11 will be released on October 5 as a free upgrade to Windows 10, but the rollout is going to be staggered, so don’t expect to see it on your screen immediately unless you buy a new device — such as Microsoft’s own Surface Pro 8, Surface Pro X, Surface Go 3 or the innovative new Surface Laptop Studio.

News: WhatsApp will stop working on some Android phones

Another year is about to end in the next three months, which means there is another cycle of WhatsApp’s end of support for some Android smartphones and iPhones. After November 1, 2021, the messaging app will not work on some of the Android versions. WhatsApp is used to removing the support for specific Android versions. This is a common technique because developers always prefer to support the newest OS updates, and it’s hard to always support old versions. It’s the case of Android OS 4.0.4 and older versions: WhatsApp has announced that they will no longer support Android phones running those versions after a new WhatsApp beta for Android update.Read more: This WhatsApp feature lets users quickly access important messagesWhat can you do to continue using WhatsApp on those versions? Unfortunately, you won’t be able to update WhatsApp after November 1, 2021, and your current WhatsApp update is going to expire after a certain date.You need to switch to a new Android device on a supported Android version if your device is old, so be sure to back up your chat history. Note that WhatsApp is also going to support chat history migration from Android to iOS in a future update if you’re interested to switch to iPhone.The post WhatsApp will stop working on some Android phones appeared first on ARY NEWS.from ScienceTechnology – ARY NEWS https://ift.tt/3uirKns https://ift.tt/eA8V8J

Another year is about to end in the next three months, which means there is another cycle of WhatsApp’s end of support for some Android smartphones and iPhones. After November 1, 2021, the messaging app will not work on some of the Android versions. 

WhatsApp is used to removing the support for specific Android versions. This is a common technique because developers always prefer to support the newest OS updates, and it’s hard to always support old versions. It’s the case of Android OS 4.0.4 and older versions: WhatsApp has announced that they will no longer support Android phones running those versions after a new WhatsApp beta for Android update.

Read more: This WhatsApp feature lets users quickly access important messages

What can you do to continue using WhatsApp on those versions? Unfortunately, you won’t be able to update WhatsApp after November 1, 2021, and your current WhatsApp update is going to expire after a certain date.

You need to switch to a new Android device on a supported Android version if your device is old, so be sure to back up your chat history. Note that WhatsApp is also going to support chat history migration from Android to iOS in a future update if you’re interested to switch to iPhone.

The post WhatsApp will stop working on some Android phones appeared first on ARY NEWS.

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News: How a plant virus could help stop cancers from reaching the lungs

Using a virus that grows in black-eyed pea plants, nanoengineers at the University of California San Diego developed a new treatment that could keep metastatic cancers at bay from the lungs.The treatment not only slowed tumor growth in the lungs of mice with either metastatic breast cancer or melanoma, it also prevented or drastically minimized the spread of these cancers to the lungs of healthy mice that were challenged with the disease.The research was published Sept. 14 in the journal Advanced Science.Cancer spread to the lungs is one of the most common forms of metastasis in various cancers. Once there, it is extremely deadly and difficult to treat.Researchers at the UC San Diego Jacobs School of Engineering developed an experimental treatment that combats this spread. It involves a bodily injection of a plant virus called the cowpea mosaic virus. The virus is harmless to animals and humans, but it still registers as a foreign invader, thus triggering an immune response that could make the body more effective at fighting cancer.The idea is to use the plant virus to help the body’s immune system recognize and destroy cancer cells in the lungs. The virus itself is not infectious in our bodies, but it has all these danger signals that alarm immune cells to go into attack mode and search for a pathogen, said Nicole Steinmetz, professor of nanoengineering at UC San Diego and director of the university’s Center for Nano-ImmunoEngineering.To draw this immune response to lung tumors, Steinmetz’s lab engineered nanoparticles made from the cowpea mosaic virus to target a protein in the lungs. The protein, called S100A9, is expressed and secreted by immune cells that help fight infection in the lungs. And there is another reason that motivated Steinmetz’s team to target this protein: overexpression of S100A9 has been observed to play a role in tumor growth and spread.“For our immunotherapy to work in the setting of lung metastasis, we need to target our nanoparticles to the lung,” said Steinmetz. “Therefore, we created these plant virus nanoparticles to home in on the lungs by making use of S100A9 as the target protein. Within the lung, the nanoparticles recruit immune cells so that the tumors don’t take.”“Because these nanoparticles tend to localize in the lungs, they can change the tumor microenvironment there to become more adept at fighting off cancer — not just established tumors, but future tumors as well,” said Eric Chung, a bioengineering Ph.D. student in Steinmetz’s lab who is one of the co-first authors on the paper.To make the nanoparticles, the researchers grew black-eyed pea plants in the lab, infected them with cowpea mosaic virus, and harvested the virus in the form of ball-shaped nanoparticles. They then attached S100A9-targeting molecules to the surfaces of the particles.The researchers performed both prevention and treatment studies. In the prevention studies, they first injected the plant virus nanoparticles into the bloodstreams of healthy mice, and then later injected either triple negative breast cancer or melanoma cells in these mice. Treated mice showed a dramatic reduction in the cancers spreading to their lungs compared to untreated mice.In the treatment studies, the researchers administered the nanoparticles to mice with metastatic tumor in their lungs. These mice exhibited smaller lung tumors and survived longer than untreated mice.What’s remarkable about these results, the researchers point out, is that they show efficacy against extremely aggressive cancer cell lines. “So any change in survival or lung metastasis is pretty striking,” said Chung. “And the fact that we get the level of prevention that we do is really, really amazing.”Steinmetz envisions that such a treatment could be especially helpful to patients after they have had a cancerous tumor removed. “It wouldn’t be meant as an injection that’s given to everyone to prevent lung tumors. Rather, it would be given to patients who are at high risk of their tumors growing back as a metastatic disease, which often manifests in the lung. This would offer their lungs protection against cancer metastasis,” she said.Before the new treatment can reach that stage, the researchers need to do more detailed immunotoxicity and pharmacology studies. Future studies will also explore combining this with other treatments such as chemotherapy, checkpoint drugs or radiation.Paper: “S100A9-Targeted Cowpea Mosaic Virus as a Prophylactic and Therapeutic Immunotherapy Against Metastatic Breast Cancer and Melanoma.” In addition to Young Hun (Eric) Chung, co-first authors of the study include Jooneon Park and Hui Cai. Nicole Steinmetz serves as the corresponding author of this work.The post How a plant virus could help stop cancers from reaching the lungs appeared first on ARY NEWS.from ScienceTechnology – ARY NEWS https://ift.tt/3ETA6H1 https://ift.tt/eA8V8J

Using a virus that grows in black-eyed pea plants, nanoengineers at the University of California San Diego developed a new treatment that could keep metastatic cancers at bay from the lungs.

The treatment not only slowed tumor growth in the lungs of mice with either metastatic breast cancer or melanoma, it also prevented or drastically minimized the spread of these cancers to the lungs of healthy mice that were challenged with the disease.

The research was published Sept. 14 in the journal Advanced Science.

Cancer spread to the lungs is one of the most common forms of metastasis in various cancers. Once there, it is extremely deadly and difficult to treat.

Researchers at the UC San Diego Jacobs School of Engineering developed an experimental treatment that combats this spread. It involves a bodily injection of a plant virus called the cowpea mosaic virus. The virus is harmless to animals and humans, but it still registers as a foreign invader, thus triggering an immune response that could make the body more effective at fighting cancer.

The idea is to use the plant virus to help the body’s immune system recognize and destroy cancer cells in the lungs. The virus itself is not infectious in our bodies, but it has all these danger signals that alarm immune cells to go into attack mode and search for a pathogen, said Nicole Steinmetz, professor of nanoengineering at UC San Diego and director of the university’s Center for Nano-ImmunoEngineering.

To draw this immune response to lung tumors, Steinmetz’s lab engineered nanoparticles made from the cowpea mosaic virus to target a protein in the lungs. The protein, called S100A9, is expressed and secreted by immune cells that help fight infection in the lungs. And there is another reason that motivated Steinmetz’s team to target this protein: overexpression of S100A9 has been observed to play a role in tumor growth and spread.

“For our immunotherapy to work in the setting of lung metastasis, we need to target our nanoparticles to the lung,” said Steinmetz. “Therefore, we created these plant virus nanoparticles to home in on the lungs by making use of S100A9 as the target protein. Within the lung, the nanoparticles recruit immune cells so that the tumors don’t take.”

“Because these nanoparticles tend to localize in the lungs, they can change the tumor microenvironment there to become more adept at fighting off cancer — not just established tumors, but future tumors as well,” said Eric Chung, a bioengineering Ph.D. student in Steinmetz’s lab who is one of the co-first authors on the paper.

To make the nanoparticles, the researchers grew black-eyed pea plants in the lab, infected them with cowpea mosaic virus, and harvested the virus in the form of ball-shaped nanoparticles. They then attached S100A9-targeting molecules to the surfaces of the particles.

The researchers performed both prevention and treatment studies. In the prevention studies, they first injected the plant virus nanoparticles into the bloodstreams of healthy mice, and then later injected either triple negative breast cancer or melanoma cells in these mice. Treated mice showed a dramatic reduction in the cancers spreading to their lungs compared to untreated mice.

In the treatment studies, the researchers administered the nanoparticles to mice with metastatic tumor in their lungs. These mice exhibited smaller lung tumors and survived longer than untreated mice.

What’s remarkable about these results, the researchers point out, is that they show efficacy against extremely aggressive cancer cell lines. “So any change in survival or lung metastasis is pretty striking,” said Chung. “And the fact that we get the level of prevention that we do is really, really amazing.”

Steinmetz envisions that such a treatment could be especially helpful to patients after they have had a cancerous tumor removed. “It wouldn’t be meant as an injection that’s given to everyone to prevent lung tumors. Rather, it would be given to patients who are at high risk of their tumors growing back as a metastatic disease, which often manifests in the lung. This would offer their lungs protection against cancer metastasis,” she said.

Before the new treatment can reach that stage, the researchers need to do more detailed immunotoxicity and pharmacology studies. Future studies will also explore combining this with other treatments such as chemotherapy, checkpoint drugs or radiation.

Paper: “S100A9-Targeted Cowpea Mosaic Virus as a Prophylactic and Therapeutic Immunotherapy Against Metastatic Breast Cancer and Melanoma.” In addition to Young Hun (Eric) Chung, co-first authors of the study include Jooneon Park and Hui Cai. Nicole Steinmetz serves as the corresponding author of this work.

The post How a plant virus could help stop cancers from reaching the lungs appeared first on ARY NEWS.

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News: New tech to prevent Li-ion battery fires

Materials scientists from Nanyang Technological University Singapore have found a way to prevent internal short-circuits, the main cause of fires in Li-ion batteries.Billions of Li-ion batteries are produced annually for use in mobile phones, laptops, personal mobile devices, and the huge battery packs of electric vehicles and aircraft.This global battery demand is set to grow, with electric vehicles alone requiring up to 2,700 GWh worth of Li-ion batteries a year by 2030, equivalent to some 225 billion mobile phone batteries.Even with an estimated failure rate of less than one-in-a-million, in 2020 there were 26 power-assisted bicycle (PAB) fires and 42 cases of personal mobility device fires in Singapore.In most Li-ion battery fires, the cause is due to a build-up of lithium deposits known as dendrites (tiny wire-like tendrils) that cross the separator between the positive (cathode) and negative (anode) electrodes of the battery when it is being charged, causing a short-circuit leading to an uncontrolled chemical fire.To prevent such battery fires, NTU scientists invented a patent-pending “anti-short layer” that can be easily added inside a Li-ion battery, preventing any future short-circuits from occurring during the charging process.This concept is akin to adding a slice of cheese to a hamburger’s meat patty in between the buns, thus the new “anti-short layer” can be rapidly adopted in current battery manufacturing.The post New tech to prevent Li-ion battery fires appeared first on ARY NEWS.from ScienceTechnology – ARY NEWS https://ift.tt/3i3pzyT https://ift.tt/2XRW1ha

Materials scientists from Nanyang Technological University Singapore have found a way to prevent internal short-circuits, the main cause of fires in Li-ion batteries.

Billions of Li-ion batteries are produced annually for use in mobile phones, laptops, personal mobile devices, and the huge battery packs of electric vehicles and aircraft.

This global battery demand is set to grow, with electric vehicles alone requiring up to 2,700 GWh worth of Li-ion batteries a year by 2030, equivalent to some 225 billion mobile phone batteries.

Even with an estimated failure rate of less than one-in-a-million, in 2020 there were 26 power-assisted bicycle (PAB) fires and 42 cases of personal mobility device fires in Singapore.

In most Li-ion battery fires, the cause is due to a build-up of lithium deposits known as dendrites (tiny wire-like tendrils) that cross the separator between the positive (cathode) and negative (anode) electrodes of the battery when it is being charged, causing a short-circuit leading to an uncontrolled chemical fire.

To prevent such battery fires, NTU scientists invented a patent-pending “anti-short layer” that can be easily added inside a Li-ion battery, preventing any future short-circuits from occurring during the charging process.

This concept is akin to adding a slice of cheese to a hamburger’s meat patty in between the buns, thus the new “anti-short layer” can be rapidly adopted in current battery manufacturing.

The post New tech to prevent Li-ion battery fires appeared first on ARY NEWS.

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News: Cartona gets $4.5M pre-Series A to connect retailers with suppliers in Egypt

image Credit: CartonaYear-old startup Capiter announced last week that it raised a $33 million Series A to digitize Egypt’s traditional offline retail market.It’s looking to take a large pie in the budding e-commerce and retail play, where multiple startups are pulling their weight including Cartona, also a year-old startup out of Egypt.Today, Cartona is announcing that it has raised a $4.5 million pre-Series A funding round to connect retailers and manufacturers via an application.The company confirmed that Dubai-based venture capital firm Global Ventures led the round, with Pan-African firm Kepple Africa, T5 Capital and angel investors also participating.Cairo-based Cartona, founded in August 2020, focuses on solving the supply-chain and operational challenges of players in the fast-moving consumer goods (FMCG) industry by helping buyers access products from sellers on a single platform.Buyers, in this case, are retailers, while sellers are FMCG companies, distributors and wholesalers.The problem retailers in Egypt and most of Africa face mainly revolves around limited access to suppliers. There are also issues around transparency in market prices, which are dependent on traditional logistical capabilities.For suppliers, the lack of data and inability to make data-backed decisions to improve margins and aid growth add up to unoptimized warehouses. “The trade market is completely inefficient and it’s not good for the supplier nor the manufacturers, and it’s definitely not good for retailers,” CEO Mahmoud Talaat told TechCrunch in an interview. “So we came up with the idea of Cartona, which is basically a fully light-asset model that connects manufacturers and wholesalers to retailers.”Talaat founded the company alongside Mahmoud Abdel-Fattah. Before Cartona, Abdel-Fattah founded Speakol, a MENA-focused adtech platform serving 60 million monthly users, while Talaat was the chief commercial officer of agriculture company Lamar Egypt.Cartona works as an asset-light marketplace. On the platform, grocery retailers can get orders from a curated network of sellers. The company says this way, it can provide visibility through real-time price comparisons and clarity on delivery times.Also, FMCGs and suppliers can optimize their go-to-market execution through the use of data and analytics. Cartona tops it off by providing embedded finance and access to credit to retailers and suppliers.Cartona makes money through all these processes. It takes a commission on orders made, charges suppliers for running advertising to merchants (since they compete for the latter’s attention), and provides market insights on buyer behavior, price competition and market share.“It is time to capitalize on technology beyond warehouses and trucks. Data and technology will transform traditional retail to a digitally native one, which in return will drastically improve the supply chain efficiency,” Abdel-Fattah said about how the company sells information to retailers and suppliers.Cartona has over 30,000 merchants on its platform. Together, they have processed more than 400,000 orders with an annualized gross merchandise value of EGP 1 billion (~$64 million). Cartona also works with more than 1,000 distributors, wholesalers and 100 FMCG companies, offering consumers more than 10,000 products, including dry, fresh and frozen food.The company’s business and revenue model is similar to other companies in this space, but the main difference lies in whether they own assets or not.Taking a look at the players in Egypt, for instance, MaxAB operates its warehouses and fleets; Capiter uses a hybrid model in which it rents these assets and owns inventory when dealing with high-turnover products. But Cartona solely manages an asset-light model.The CEO tells me that he thinks this model works best for all the stakeholders involved in the retail market. He argues that not owning assets and leasing the ones on the ground shows that the company is trying to improve the operations of existing suppliers and merchants instead of displacing them.“I believe that the infrastructure already exists. We already have many warehouses, many small and medium-sized entrepreneurs, and wholesalers and distributors and companies that have a lot of assets. If you want to fix the problem, we think one should enable the people who are strategically located in small streets all over Egypt and have the infrastructure but don’t have the technology needed to optimize their warehouses and carts.”The current margins for suppliers with warehouses are slim, and Cartona provides the technology — an inventory and ordering system — to provide efficiency in its supply chain.The general partner at lead investor Global Ventures, Basil Moftah, said in a statement that Cartona’s technology and not owning inventory proved critical in the firm’s decision to back the company.“The trade market is one of the most sophisticated, yet [it is] characterized by multiple critical inefficiencies across the value chain,” he said. “Cartona’s asset-light approach tackles those inefficiencies by optimizing the trade process in unique ways and does so with minimal capital spent.”Proceeds of the investment focus on improving this technology, Talaat said. In addition, Cartona is expanding its team and operations beyond two cities in Egypt — Cairo and Alexandria — to other parts.A longer-term plan might include horizontal and vertical product expansion into pharmaceuticals, electronics and fashion.

Cartona

image Credit: Cartona

Year-old startup Capiter announced last week that it raised a $33 million Series A to digitize Egypt’s traditional offline retail market.

It’s looking to take a large pie in the budding e-commerce and retail play, where multiple startups are pulling their weight including Cartona, also a year-old startup out of Egypt.

Today, Cartona is announcing that it has raised a $4.5 million pre-Series A funding round to connect retailers and manufacturers via an application.

The company confirmed that Dubai-based venture capital firm Global Ventures led the round, with Pan-African firm Kepple Africa, T5 Capital and angel investors also participating.

Cairo-based Cartona, founded in August 2020, focuses on solving the supply-chain and operational challenges of players in the fast-moving consumer goods (FMCG) industry by helping buyers access products from sellers on a single platform.

Buyers, in this case, are retailers, while sellers are FMCG companies, distributors and wholesalers.

The problem retailers in Egypt and most of Africa face mainly revolves around limited access to suppliers. There are also issues around transparency in market prices, which are dependent on traditional logistical capabilities.

For suppliers, the lack of data and inability to make data-backed decisions to improve margins and aid growth add up to unoptimized warehouses. 

“The trade market is completely inefficient and it’s not good for the supplier nor the manufacturers, and it’s definitely not good for retailers,” CEO Mahmoud Talaat told TechCrunch in an interview. “So we came up with the idea of Cartona, which is basically a fully light-asset model that connects manufacturers and wholesalers to retailers.”

Talaat founded the company alongside Mahmoud Abdel-Fattah. Before Cartona, Abdel-Fattah founded Speakol, a MENA-focused adtech platform serving 60 million monthly users, while Talaat was the chief commercial officer of agriculture company Lamar Egypt.

Cartona works as an asset-light marketplace. On the platform, grocery retailers can get orders from a curated network of sellers. The company says this way, it can provide visibility through real-time price comparisons and clarity on delivery times.

Also, FMCGs and suppliers can optimize their go-to-market execution through the use of data and analytics. Cartona tops it off by providing embedded finance and access to credit to retailers and suppliers.

Cartona makes money through all these processes. It takes a commission on orders made, charges suppliers for running advertising to merchants (since they compete for the latter’s attention), and provides market insights on buyer behavior, price competition and market share.

“It is time to capitalize on technology beyond warehouses and trucks. Data and technology will transform traditional retail to a digitally native one, which in return will drastically improve the supply chain efficiency,” Abdel-Fattah said about how the company sells information to retailers and suppliers.

Cartona has over 30,000 merchants on its platform. Together, they have processed more than 400,000 orders with an annualized gross merchandise value of EGP 1 billion (~$64 million). Cartona also works with more than 1,000 distributors, wholesalers and 100 FMCG companies, offering consumers more than 10,000 products, including dry, fresh and frozen food.

The company’s business and revenue model is similar to other companies in this space, but the main difference lies in whether they own assets or not.

Taking a look at the players in Egypt, for instance, MaxAB operates its warehouses and fleets; Capiter uses a hybrid model in which it rents these assets and owns inventory when dealing with high-turnover products. But Cartona solely manages an asset-light model.

The CEO tells me that he thinks this model works best for all the stakeholders involved in the retail market. He argues that not owning assets and leasing the ones on the ground shows that the company is trying to improve the operations of existing suppliers and merchants instead of displacing them.

I believe that the infrastructure already exists. We already have many warehouses, many small and medium-sized entrepreneurs, and wholesalers and distributors and companies that have a lot of assets. If you want to fix the problem, we think one should enable the people who are strategically located in small streets all over Egypt and have the infrastructure but don’t have the technology needed to optimize their warehouses and carts.”

The current margins for suppliers with warehouses are slim, and Cartona provides the technology — an inventory and ordering system — to provide efficiency in its supply chain.

The general partner at lead investor Global Ventures, Basil Moftah, said in a statement that Cartona’s technology and not owning inventory proved critical in the firm’s decision to back the company.

“The trade market is one of the most sophisticated, yet [it is] characterized by multiple critical inefficiencies across the value chain,” he said. Cartona’s asset-light approach tackles those inefficiencies by optimizing the trade process in unique ways and does so with minimal capital spent.”

Proceeds of the investment focus on improving this technology, Talaat said. In addition, Cartona is expanding its team and operations beyond two cities in Egypt — Cairo and Alexandria — to other parts.

A longer-term plan might include horizontal and vertical product expansion into pharmaceuticals, electronics and fashion.

News: Here’s how you can upgrade to Windows 11 early

Microsoft will begin rolling out Windows 11 on October 5.  However, the company has finalised the new version and released it to its Release Preview channel.You can switch to the Release Preview in Windows 10 and get the free Windows 11 upgrade early.Here’s how you can get the free Windows 11 upgrade:First you need to see if your PC is compatible with Windows 11 using Microsoft’s PC Health App (download here).If your PC is compatible, you will have to register as a Windows Insider at Microsoft’s site to get the upgrade early.On the existing 10 PC, go to Settings > Update & Security > Windows Insider ProgramClick the “Get Started” button and link the Microsoft account you used to sign up to be a Windows InsiderSelect the Release Preview ring when asked to pick your Insider settingsAgree to Microsoft terms and then reboot your computerGo to Settings > Update & Security, and you will see a new banner with the option update to Windows 11Download and install option and follow the prompts to get the new operating system earlyAfter upgrading to Windows 11, you can then go to Settings > Windows Update and select “Stop getting preview builds” to unenroll from the preview updates for Windows 11 and remain on the final version.The post Here’s how you can upgrade to Windows 11 early appeared first on ARY NEWS.from ScienceTechnology – ARY NEWS https://ift.tt/3o6gw49 https://ift.tt/3zG7xc0

Microsoft will begin rolling out Windows 11 on October 5.  However, the company has finalised the new version and released it to its Release Preview channel.

You can switch to the Release Preview in Windows 10 and get the free Windows 11 upgrade early.

Here’s how you can get the free Windows 11 upgrade:

  • First you need to see if your PC is compatible with Windows 11 using Microsoft’s PC Health App (download here).
  • If your PC is compatible, you will have to register as a Windows Insider at Microsoft’s site to get the upgrade early.
  • On the existing 10 PC, go to Settings > Update & Security > Windows Insider Program

  • Click the “Get Started” button and link the Microsoft account you used to sign up to be a Windows Insider
  • Select the Release Preview ring when asked to pick your Insider settings
  • Agree to Microsoft terms and then reboot your computer
  • Go to Settings > Update & Security, and you will see a new banner with the option update to Windows 11
  • Download and install option and follow the prompts to get the new operating system early

After upgrading to Windows 11, you can then go to Settings > Windows Update and select “Stop getting preview builds” to unenroll from the preview updates for Windows 11 and remain on the final version.

The post Here’s how you can upgrade to Windows 11 early appeared first on ARY NEWS.

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News: Robinhood testing crypto wallet, cryptocurrency transfer features

Robinhood Markets is testing new crypto wallet and cryptocurrency transfer features for its app which would allow customers to send and receive digital currencies such as bitcoin, Bloomberg News reported on Monday.A beta version of its iPhone app showed the company’s work on such features, the report said.There was also a hidden image showing a waitlist page for users signing up for a crypto wallet feature, the report added.A spokesperson for Robinhood declined to comment.The company’s retail shareholders have long waited for a crypto wallet. A day before the brokerage announced its first quarterly results last month, the top question on Say, a platform that lets companies crowdsource questions from retail investors, was whether the brokerage was getting such a wallet.The trading app operator has bet big on the retail investor interest in the digital currency space. Earlier this month, the company said it would roll out crypto recurring investments, allowing users to buy digital coins commission-free and with as little as $1 on a schedule of their choice.The post Robinhood testing crypto wallet, cryptocurrency transfer features appeared first on ARY NEWS.


Robinhood Markets is testing new crypto wallet and cryptocurrency transfer features for its app which would allow customers to send and receive digital currencies such as bitcoin, Bloomberg News reported on Monday.

A beta version of its iPhone app showed the company’s work on such features, the report said.

There was also a hidden image showing a waitlist page for users signing up for a crypto wallet feature, the report added.

A spokesperson for Robinhood declined to comment.

The company’s retail shareholders have long waited for a crypto wallet. A day before the brokerage announced its first quarterly results last month, the top question on Say, a platform that lets companies crowdsource questions from retail investors, was whether the brokerage was getting such a wallet.

The trading app operator has bet big on the retail investor interest in the digital currency space. Earlier this month, the company said it would roll out crypto recurring investments, allowing users to buy digital coins commission-free and with as little as $1 on a schedule of their choice.

The post Robinhood testing crypto wallet, cryptocurrency transfer features appeared first on ARY NEWS.

News: Upcoming PUBG game is being developed on Unreal Engine 5: report

The developers of the PUBG mobile survival gaming franchise are reportedly availing Unreal Engine 5 for its upcoming instalment.It is no secret that the sequel of the acclaimed is in development. The project rumoured to be titled PUBG 2, is expected to be released next year provided there are no obstacles in the team’s way.The company, as of this moment, has not announced the release date and title for the project.A Twitter user by the name of PlayerIGN has come up with rumours about the upcoming PlayerUnknown’s Battleground sequel.He shared a picture of the job opening advertisement in which PUBG Corporation is hiring a technical animator and a technical art director for an “announced project”.NEW UE5 PUBG game:PUBG Amsterdam’s hiring to build a new AAA Unreal Engine 5 “UNANNOUNCED PROJECT” game.A PUBG2 project upgrading to UE5 was discussed a few months ago via internal sources.Also from diff recent leak at Nvidia, we know there’s a WIP Krafton game called “X1.” pic.twitter.com/oQKuyN3NQ1— PlayerIGN (@PlayerIGN) September 22, 2021Art Director, Game Director and Producers to execute a AAA realisation of the project with Unreal Engine 5,” the advertisement read.Read More: PUBG Mobile reports 1 billion accumulated downloads since launchThe job advertisement is pretty much summing up that the PUBG Corporation will now be using Unreal Engine 5 instead of its predecessor. Krafton is yet to make it official.Unreal Engine will be allowing the developers to include better graphics, high-tech performances and allows the company to provide content that will make the player’s money and value worthwhile.The post Upcoming PUBG game is being developed on Unreal Engine 5: report appeared first on ARY NEWS.from ScienceTechnology – ARY NEWS https://ift.tt/3zEj9MP https://ift.tt/eA8V8J

The developers of the PUBG mobile survival gaming franchise are reportedly availing Unreal Engine 5 for its upcoming instalment.

It is no secret that the sequel of the acclaimed is in development. The project rumoured to be titled PUBG 2, is expected to be released next year provided there are no obstacles in the team’s way.

The company, as of this moment, has not announced the release date and title for the project.

A Twitter user by the name of PlayerIGN has come up with rumours about the upcoming PlayerUnknown’s Battleground sequel.

He shared a picture of the job opening advertisement in which PUBG Corporation is hiring a technical animator and a technical art director for an “announced project”.

NEW UE5 PUBG game:

PUBG Amsterdam’s hiring to build a new AAA Unreal Engine 5 “UNANNOUNCED PROJECT” game.

A PUBG2 project upgrading to UE5 was discussed a few months ago via internal sources.

Also from diff recent leak at Nvidia, we know there’s a WIP Krafton game called “X1.” pic.twitter.com/oQKuyN3NQ1

— PlayerIGN (@PlayerIGN) September 22, 2021

Art Director, Game Director and Producers to execute a AAA realisation of the project with Unreal Engine 5,” the advertisement read.

Read More: PUBG Mobile reports 1 billion accumulated downloads since launch

The job advertisement is pretty much summing up that the PUBG Corporation will now be using Unreal Engine 5 instead of its predecessor. Krafton is yet to make it official.

Unreal Engine will be allowing the developers to include better graphics, high-tech performances and allows the company to provide content that will make the player’s money and value worthwhile.

The post Upcoming PUBG game is being developed on Unreal Engine 5: report appeared first on ARY NEWS.

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News: How do you help someone with their leg bitten off by a shark?

How do you help someone with their leg bitten off by a shark? Groundbreaking research by an Australian medic-surfer has uncovered a simple way to stop bleeding and save lives.Find the middle point between the hip and the genitals, make a fist and push as hard as you can.Shark attacks are rare but on the increase Down Under, due in large part to more people being in the water.So surfer and Australian National University medical school dean Nicholas Taylor set out to discover how to reduce fatalities in the event of an attack.Many fatal shark bites occur around the legs, leaving the victim to bleed to death despite making it back to shore.In a study published by Emergency Medicine Australasia, Taylor found that a simple technique to compress the femoral artery was much more effective in stopping bleeding than traditionally-used tourniquets.His study showed that by making a fist and pressing down on the artery around 89.7% of blood flow was stopped, versus 43.8% using a surfboard leash as a make-shift tourniquet.The technique worked equally well with the patient wearing a wetsuit and without.“I knew from my background in emergency medicine if people have massive bleeding from their leg, you can push very hard on the femoral artery and you can pretty much cut the entire blood flow of the leg that way,” he said in a statement released by the university on Friday.“It is easy to do and easy to remember — push hard between the hip and the bits and you could save a life.”Taylor hopes the technique will become widely known among Australia’s roughly half a million surfers, for whom shark encounters are less uncommon.“I want posters at beaches. I want to get it out in the surf community. I want people to know that if someone gets bitten you can pull out the patient, push as hard as you can in this midpoint spot and it can stop almost all of the blood flow,” he said.The post How do you help someone with their leg bitten off by a shark? appeared first on ARY NEWS.from ScienceTechnology – ARY NEWS https://ift.tt/3CKBREi https://ift.tt/eA8V8J

How do you help someone with their leg bitten off by a shark? Groundbreaking research by an Australian medic-surfer has uncovered a simple way to stop bleeding and save lives.

Find the middle point between the hip and the genitals, make a fist and push as hard as you can.

Shark attacks are rare but on the increase Down Under, due in large part to more people being in the water.

So surfer and Australian National University medical school dean Nicholas Taylor set out to discover how to reduce fatalities in the event of an attack.

Many fatal shark bites occur around the legs, leaving the victim to bleed to death despite making it back to shore.

In a study published by Emergency Medicine Australasia, Taylor found that a simple technique to compress the femoral artery was much more effective in stopping bleeding than traditionally-used tourniquets.

His study showed that by making a fist and pressing down on the artery around 89.7% of blood flow was stopped, versus 43.8% using a surfboard leash as a make-shift tourniquet.

The technique worked equally well with the patient wearing a wetsuit and without.

“I knew from my background in emergency medicine if people have massive bleeding from their leg, you can push very hard on the femoral artery and you can pretty much cut the entire blood flow of the leg that way,” he said in a statement released by the university on Friday.

“It is easy to do and easy to remember — push hard between the hip and the bits and you could save a life.”

Taylor hopes the technique will become widely known among Australia’s roughly half a million surfers, for whom shark encounters are less uncommon.

“I want posters at beaches. I want to get it out in the surf community. I want people to know that if someone gets bitten you can pull out the patient, push as hard as you can in this midpoint spot and it can stop almost all of the blood flow,” he said.

The post How do you help someone with their leg bitten off by a shark? appeared first on ARY NEWS.

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